Research Scientist III - Immunoassay Development

Summary

The Immunoassay Research and Development group at Grifols Diagnostic Solutions in Emeryville, CA is seeking a experienced immunoassay development scientist to help develop ultrasensitive assays for multiple commercial indications.

Research Scientist III will lead and perform innovative research and work collaboratively with other scientific team members within R&D to design, develop, and verify immunoassays. This scientist will initiate, execute, and interpret scientistic research projects pertaining to immunoassay development, such as ELISA and/or other proprietary immune platforms. This scientist will work cross functionally with technical teams within and outside of R&D. This scientist will mentor or manager junior technical staff in pursuit of better and more sensitive immunoassays.

Come join a vibrant immunoassay development team and have a direct impact on human health!

Primary Responsibilities

• Plans multifaceted projects and incorporates multiple experimental approaches appropriately.
• Leads and carries out immunoassay design, development, and validation using novel and commercial recombinant proteins for multiple indications and commercial applications.
• Leads selection and bioconjugation of recombinant proteins to develop reagents and tools for immunoassays.
• Evaluates protein stability, stoichiometry, and purity using modern analytical techniques and develops protein, reagent and assay formulations.
• Develops assay product prototypes for multiple indications and transfers them to process development and manufacturing teams.
• Independently or with team members, plans R&D projects requiring initiative and judgement within defined procedures and practices.
• Independently selects methodological approaches and specific methods to achieve project objectives. 
• Exercises judgment and initiative in making research project decisions.  Performs experiments in the laboratory, as needed.
• Identifies, analyzes, and interprets project results. Communicates results and project status to key stakeholders and management. 
• Clearly communicates results and project status to key stakeholders and management in a manner that's tailored to diverse audiences.  
• Sources and interprets literature and runs database searches to aid in designing experimental studies, troubleshooting experiments, and interpreting findings. Writes original proposals for research projects and remains current on pertinent scientific topics. 
• Works cross functionally and leads collaborations within and outside of R&D, external partners, and/or CROs. 
• Prepares written reports on all phases of laboratory experimental projects.
• Authors or co-authors scientific papers and /or journal articles and technical reports. 
• Reviews and edits pertinent regulatory documents. 
• Prepares and defends patent disclosures and applications.
• May mentor, train or manage other R&D technical staff.
• Attends and participates in scientific meetings, seminars and leadership team meetings.
• Partners and collaborates with small teams in a scientific development environment.
• Plan and prioritize activities while anticipating risks and challenges, monitor progress, and deliver projects to meet timelines and milestones

Knowledge, Skills, and Abilities

• Background in protein biochemistry, structual biology, or protein biophysics
• Subject matter expert in immunoassay development and validation, including antibody development and screening, ELISA, western blot, immunostaining, BLI
• Experience with DOE for buffer formulation and relevant sofrware packages
• Experience bringing tests for FDA and/or EU approval is a plus
• Experience in method development and optimization of antibody/antigen modification, bioconjugation and coupling onto solid phases; experience with magnetic particles is a plus
• Analytical assay development, qualification and validation requirements to comply with current regulatory standards
• Ability to operate laboratory equipment, that may include BLI, DLS, ELISA, and protein quantification platforms                                                                                                                                                                                                                                                                 
• Ability to become familiar with relevant scientific literature and represent the research team at meetings and deliver concise scientific presentations. 
• Comfortable with handling biohazardous and infectious samples
• Excellent interpersonal and communication skills and experience working in collaborative settings
• Data analysis, project planning, judgement in making project decisions
• Management experience or experience in supervising laboratory training with interns, graduate students, technical staff or post-doctoral students is highly preferred. 
• Experience leading projects and achieving project milestones is highly preferred.       
• Experience with immunology, infectious diseases, and oncology is highly preferred.    
• Background in immunology and infectious diseases is a plus  
• Background in establishing and utilizing large data bases is a plus           

Education
PhD. degree in Biochemistry, Chemistry, Microbiology, Biology or other life science field 

Experience

8+ years laboratory experience post Ph.D. 

Equivalency

Depending on the area of assignment, directly related experience or a combination of directly related education and experience and/or competencies may be considered in place of the stated requirements.  Example:  If a job level requires a Bachelor’s degree plus 4 years of experience, an equivalency could include 8 years of experience, an Associate’s degree with 6 years of experience, or a Master’s degree with 2 years of experience.        

Pay Scale

The estimated pay scale for Research Scientist III role based in Emeryville, California is $148,320 to $185,400. Additionally, the position is eligible to participate in up to 15% of the company bonus pool. We offer a wide variety of benefits including, but not limited to: Medical, Dental, Vision, PTO, up to 5% 401(K) match and tuition reimbursement. Currently, the first year PTO accrual for this role is 120 hours per year. Then, after completion of 365 days of employment PTO accrual for this role will increase to 160 hours per year. Final compensation packages will ultimately depend on education, experience, skillset, knowledge, where the role is performed, internal equity and market data. We are committed to offering our employees opportunities for professional growth and career progression. Grifols is a global healthcare organization with employees in 30 countries focused on patient health and providing impactful results. Since our humble beginnings in 1909, Grifols has been a family company that prides itself on its family-like culture. Our company has more than tripled over the last 10 years, and you can grow with us!

This job description is intended to present the general content and requirements for the performance of this job.  The description is not to be construed as an exhaustive statement of duties, responsibilities, or requirements.  Managers and supervisors may assign other duties as needed.

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Third Party Agency and Recruiter Notice:

Agencies that present a candidate to Grifols must have an active, nonexpired, Grifols Agency Master Services Agreement with the Grifols Talent Acquisition Department. Additionally, agencies may only submit candidates to positions that they have been engaged to work on by a Grifols Recruiter. All resumes must be sent to a Grifols Recruiter under these terms or they will be considered a Grifols candidate.

Grifols provides equal employment opportunities to applicants and employees without regard to race; color; sex; gender identity; sexual orientation; religious practices and observances; national origin; pregnancy, childbirth, or related medical conditions; status as a protected veteran or spouse/family member of a protected veteran; or disability.  We will consider for employment all qualified applicants in a manner consistent with the requirements of all applicable laws, including but not limited to, the California Fair Chance Act, the Los Angeles County Fair Chance Ordinance for Employers, and the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.

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Location: NORTH AMERICA : USA : CA-Emeryville:USEMV - Emeryville CA-Headquarters 

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